Parp2 CLIA Kit for Mouse(Mus musculus) | EIAab.comParp2 CLIA Kit for Mouse(Mus musculus)

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Parp2 (Gene name),

Poly [ADP-ribose] polymerase 2 (Protein name ), PARP2_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Parp2(Adprt2;Adprtl2;Aspartl2);

Protein name:

Poly [ADP-ribose] polymerase 2(PARP-2;mPARP-2);

Alternative:

Poly[ADP-ribose] synthase 2(pADPRT-2);NAD(+) ADP-ribosyltransferase 2(ADPRT-2);Poly[ADP-ribose] synthase 2(pADPRT-2);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Component of a base excision repair (BER) complex, containing at least XRCC1, PARP1, POLB and LRIG3. Homo- and heterodimer with PARP1.

Function:

Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

559

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

559:

IQFNFLQLW

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Mm.281482

KEGG:

mmu:11546

Pfam:

PF00644

STRING:

10090.ENSMUSP00000048877

String:

O88554

SMR:

O88554

Uniprot:

O88554

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ELISA Kit for Mouse PARP-2

Cat.:

E9945h

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Manual:

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Packing:

96T

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ELISA Kit for Mouse PARP-2

Cat.:

E9945m

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MSDS:

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Packing:

96T

CLIA Kit for Mouse PARP-2

Cat.:

U9945h

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Manual:

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96T

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CLIA Kit for Mouse PARP-2

Cat.:

U9945m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse PARP-2

Cat.:

P9945Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse PARP-2

Cat.:

P9945Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse PARP-2

Protein for Mouse PARP-2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"PARP-2, a novel mammalian DNA damage-dependent poly(ADP-ribose) polymerase."
Ame J.-C. , Rolli V. , Schreiber V. , Niedergang C. , Apiou F. , Decker P. , Muller S. , Hoeger T. , Menissier-de Murcia J. , de Murcia G.M.
J. Biol. Chem.274:17860-17868(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];CHARACTERIZATION
tissue: Embryo.
2.

"A bidirectional promoter connects the poly(ADP-ribose) polymerase 2 (PARP-2) gene to the gene for RNase P RNA. Structure and expression of the mouse PARP-2 gene."
Ame J.-C. , Schreiber V. , Fraulob V. , Dolle P. , de Murcia G.M. , Niedergang C.P.
J. Biol. Chem.276:11092-11099(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
strain: 129/Sv.
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Embryo.
4.

"pADPRT-2: a novel mammalian polymerizing(ADP-ribosyl)transferase gene related to truncated pADPRT homologues in plants and Caenorhabditis elegans."
Berghammer H. , Ebner M. , Marksteiner R. , Auer B.
FEBS Lett.449:259-263(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 9-559
strain: C57BL/6 X 129/Sv.
5.

"Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1."
Schreiber V. , Ame J.-C. , Dolle P. , Schultz I. , Rinaldi B. , Fraulob V. , Menissier-de Murcia J. , de Murcia G.M.
J. Biol. Chem.277:23028-23036(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PARP1; XRCC1; POLB AND LRIG3;POLY-ADP-RIBOSYLATION
6.

"Identification of lysines 36 and 37 of PARP-2 as targets for acetylation and auto-ADP-ribosylation."
Haenni S.S. , Hassa P.O. , Altmeyer M. , Fey M. , Imhof R. , Hottiger M.O.
Int. J. Biochem. Cell Biol.40:2274-2283(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION AT LYS-36 AND LYS-37;ADP-RIBOSYLATION AT LYS-36 AND LYS-37;MUTAGENESIS OF LYS-36 AND LYS-37

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